Description

1-Fluoro-3-Adamantanecarboxylic Acid is a high-value, fluorinated derivative of adamantane, prized for its unique structural rigidity and the introduction of a fluorine atom and a carboxylic acid functional group. This combination makes it a versatile and critical building block in advanced organic synthesis, particularly for the development of novel pharmaceutical compounds and specialty materials. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material science industries seeking to incorporate the adamantane scaffold for enhanced stability and bioavailability.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) drugs, antiviral agents, and other therapeutics where the adamantane core provides metabolic stability.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its structural properties to create compounds with specific biological activity.
• Material Science Research: Acts as a monomer or functional additive in the creation of specialty polymers, coatings, and advanced organic frameworks (e.g., MOFs) with tailored properties.
• Fluorine Chemistry Building Block: A valuable reagent for introducing both the adamantane moiety and a carboxylic acid handle into target molecules, facilitating further derivatization.
• Ligand and Catalyst Development: Employed in the design of novel ligands for catalysis or in the synthesis of organometallic complexes.
• Academic and R&D Laboratories: Used in fundamental chemical research to explore new synthetic methodologies and structure-activity relationships.

Basic Information

Product Name	1-Fluoro-3-Adamantanecarboxylic Acid
CAS No.	880-50-2
Molecular Formula	C11H15FO2
Molecular Weight	198.23 g/mol
Synonyms	1-Fluoroadamantane-3-carboxylic Acid; 3-Fluoroadamantane-1-carboxylic Acid; 1-Fluoro-3-carboxyadamantane; Adamantane-1-carboxylic acid, 3-fluoro-; 3-Fluoro-1-adamantanecarboxylic Acid; 1-Fluoro-tricyclo[3.3.1.1³,⁷]decane-3-carboxylic Acid; 1-Fluoro-3-adamantylcarboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-Adamantanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.