Description

6-Fluoro-Cinnolin-4-Ol is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the fluorine atom and cinnolinone core impart desirable biological activity and metabolic stability. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, particularly for creating new active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Material Science Precursor: Serves as a starting material for synthesizing specialized fluorinated organic compounds used in electronic materials and liquid crystals.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme inhibition and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	6-Fluoro-Cinnolin-4-Ol
CAS No.	876-90-4
Molecular Formula	C8H5FN2O
Molecular Weight	164.14 g/mol
Synonyms	6-Fluoro-4-hydroxycinnoline; 6-Fluoro-4-cinnolinol; 4-Hydroxy-6-fluorocinnoline; 6-Fluorocinnolin-4-ol; 6-Fluoro-1,2-benzodiazin-4-ol; 876-90-4; 6-Fluoro-4-cinnolinone; 6-Fluoro-4(1H)-cinnolinone
EINECS	Contact for details

Quality Control

Our 6-Fluoro-Cinnolin-4-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity determination, and is supplied with a comprehensive Certificate of Analysis (COA). We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.