Description

4-(Chloromethyl)Tolunitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive chloromethyl group and a cyano group, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzylamine or substituted benzylamine backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its structure can be incorporated into more complex bioactive molecules.
• Ligand and Catalyst Preparation: Serves as a starting material for the synthesis of specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Functional Material Development: Employed in research for creating monomers or additives for advanced polymers, liquid crystals, or electronic materials.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry teams exploring new synthetic routes and novel compound libraries.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of certain specialized dyes and organic pigments.

Basic Information

Product Name	4-(Chloromethyl)Tolunitrile
CAS No.	874-86-2
Molecular Formula	C9H8ClN
Molecular Weight	165.62 g/mol
Synonyms	4-(Chloromethyl)benzonitrile; p-(Chloromethyl)benzonitrile; 4-Cyanobenzyl chloride; p-Cyanobenzyl chloride; α-Chloro-p-tolunitrile; (4-Cyanophenyl)methyl chloride; 1-Chloromethyl-4-cyanobenzene; Benzonitrile, 4-(chloromethyl)-
EINECS	212-863-5

Quality Control

Our 4-(Chloromethyl)Tolunitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data with each shipment, including detailed Certificates of Analysis (COA) that report purity, identity, and impurity profiles. Our standard grade meets the rigorous demands of industrial synthesis, and we can support custom purity requirements for specific research or cGMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. Due to the reactive chloromethyl group, it is recommended to handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.