Description

Dimethyl trans-1,2-Cyclopropanedicarboxylate is a high-purity diester derivative of cyclopropane-1,2-dicarboxylic acid, serving as a versatile and valuable chiral building block in advanced organic synthesis. Its rigid, strained three-membered ring structure and defined stereochemistry make it a critical intermediate for constructing complex molecular architectures with high precision. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), ligands, and novel functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of prostaglandins, antiviral agents, and other bioactive molecules with cyclopropane motifs.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis, crucial for enantioselective manufacturing processes.
• Material Science Research: Monomer or precursor for developing polymers and advanced materials with unique thermal or mechanical properties.
• Organic Synthesis Reagent: Employed in ring-opening reactions, [2+1] cycloadditions, and other transformations to introduce the cyclopropane ring into target molecules.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing specific aroma chemicals with complex, stereodefined structures.

Basic Information

Product Name	Dimethyl trans-1,2-Cyclopropanedicarboxylate
CAS No.	826-35-7
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	trans-1,2-Cyclopropanedicarboxylic Acid Dimethyl Ester; (1R,2R)-1,2-Cyclopropanedicarboxylic Acid Dimethyl Ester; Dimethyl (1R,2R)-1,2-Cyclopropanedicarboxylate; Dimethyl trans-Cyclopropane-1,2-dicarboxylate; Methyl trans-1,2-Cyclopropanedicarboxylate; (R,R)-Dimethyl Cyclopropane-1,2-dicarboxylate; trans-Cyclopropane-1,2-dicarboxylic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our Dimethyl trans-1,2-Cyclopropanedicarboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR, and quantification of residual solvents. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.