Description

2-Bromo-4'-Chloroacetophenone CAS NO 825-40-1 is a versatile halogenated acetophenone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its bifunctional reactivity, featuring both a reactive carbonyl group and halogen substituents, making it an essential building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with halogenated aromatic structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, leveraging its halogenated phenyl ketone core.
• Chemical Research & Development: A valuable reagent in organic synthesis for constructing complex molecules via reactions like nucleophilic substitution, Friedel-Crafts acylation, and Grignard reactions.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of specialized dyes and organic pigments.
• Ligand & Catalyst Preparation: Used to synthesize chelating ligands for metal complexes and catalysts.

Basic Information

Product Name	2-Bromo-4'-Chloroacetophenone
CAS No.	825-40-1
Molecular Formula	C8H6BrClO
Molecular Weight	233.49 g/mol
Synonyms	1-(4-Chlorophenyl)-2-bromoethanone; 2-Bromo-1-(4-chlorophenyl)ethanone; 4'-Chloro-2-bromoacetophenone; p-Chlorophenacyl bromide; α-Bromo-4'-chloroacetophenone; 2-Bromo-4'-chloroacetophenone; Ethanone, 2-bromo-1-(4-chlorophenyl)-; Bromo(4-chlorophenyl)methanone
EINECS	Contact for details

Quality Control

Our 2-Bromo-4'-Chloroacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee supply reliability and product traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	88°C - 92°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.