Description

Isothiazole-4-Carbaldehyde is a versatile heterocyclic aldehyde building block of significant importance in advanced organic synthesis. Its unique structure, featuring both an isothiazole ring and a reactive formyl group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, anti-infectives, and other bioactive heterocycles.
• Agrochemical Synthesis: Used in the development of new-generation fungicides, herbicides, and insecticides, leveraging the bioactivity of the isothiazole moiety.
• Material Science: Serves as a building block for functional polymers, liquid crystals, and organic electronic materials due to its conjugated system and reactive aldehyde group.
• Chemical Research: Employed in academic and industrial R&D for exploring new organic reactions, catalytic processes, and as a ligand precursor in coordination chemistry.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the isothiazole ring contributes to color and stability properties.

Basic Information

Product Name	Isothiazole-4-Carbaldehyde
CAS No.	822-54-8
Molecular Formula	C4H3NOS
Molecular Weight	113.14 g/mol
Synonyms	4-Isothiazolecarboxaldehyde; 4-Formylisothiazole; Isothiazole-4-carboxaldehyde; 1,2-Thiazole-4-carboxaldehyde; 4-Carbaldehyde isothiazole; 822-54-8; 4-Isothiazolecarbaldehyde
EINECS	Contact for details

Quality Control

Our Isothiazole-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.