Description

Chloroformic Acid 2-Chloro-1-Methylethyl Ester is a specialized chloroformate ester, a key reactive intermediate in organic synthesis. Its primary value lies in its role as a versatile building block for introducing the 2-chloro-1-methylethyl (isopropylidene chloromethyl) functional group, enabling the synthesis of complex molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly in constructing ester and carbamate linkages.
• Agrochemical Synthesis: Serves as a key reagent in the production of herbicides, fungicides, and insecticides.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers and resins.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals.
• Protecting Group Chemistry: Useful for the temporary protection of alcohols and amines during multi-step synthetic sequences.
• Bioconjugation: Can be utilized for modifying biomolecules in research applications.

Basic Information

Product Name	Chloroformic Acid 2-Chloro-1-Methylethyl Ester
CAS No.	817-80-1
Molecular Formula	C5H8Cl2O2
Molecular Weight	171.02 g/mol
Synonyms	2-Chloro-1-methylethyl chloroformate; 1-Chloro-2-propyl chloroformate; Isopropylidene chloromethyl chloroformate; Chloromethyl isopropyl chloroformate; (2-Chloro-1-methylethoxy)carbonyl chloride; 2-Chloroisopropyl chloroformate; Propane, 2-chloro-1-(chloroformyloxy)-; NSC 9375
EINECS	212-451-8

Quality Control

Our Chloroformic Acid 2-Chloro-1-Methylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC or HPLC, identity confirmation (IR), and control of key impurities, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, physical properties, and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. Due to its moisture-sensitive (hygroscopic) nature, containers must be kept tightly sealed under a dry inert atmosphere (e.g., nitrogen) after opening to prevent hydrolysis and maintain purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	1.28 - 1.32 g/cm³
Refractive Index (n20D)	1.435 - 1.445

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.