Description

Tetramethylguanidine is a powerful, non-nucleophilic organic superbase with the CAS number 80-70-6. It is a critical reagent in organic synthesis, valued for its high basicity and solubility in a wide range of organic solvents. This versatile compound is essential for industries requiring efficient catalysis and deprotonation reactions, particularly in pharmaceuticals, agrochemicals, and polymer production.

Application

• Pharmaceutical Synthesis: As a catalyst and strong base in the production of active pharmaceutical ingredients (APIs), particularly for condensation and deprotonation reactions.
• Polymer Chemistry: Used as an initiator or catalyst in the production of polyurethanes, polycarbonates, and other specialty polymers.
• Agrochemical Manufacturing: Employed in the synthesis of pesticides, herbicides, and plant growth regulators.
• Organic Synthesis: A key reagent for promoting various reactions including Knoevenagel condensations, Michael additions, and the synthesis of heterocyclic compounds.
• Chemical Research & Development: Serves as a fundamental tool in R&D labs for exploring new synthetic pathways and methodologies.
• Fine Chemicals Production: Utilized in the manufacture of dyes, pigments, and other complex organic molecules.

Basic Information

Product Name	Tetramethylguanidine
CAS No.	80-70-6
Molecular Formula	C5H13N3
Molecular Weight	115.18 g/mol
Synonyms	1,1,3,3-Tetramethylguanidine; TMG; N,N,N',N'-Tetramethylguanidine; Tetramethylcarbamidine; Guanidine, N,N,N',N'-tetramethyl-; 1,1,3,3-Tetramethyl-2-aza-1,3-diaminopropene; UNII-0JQ0S2I0Q1
EINECS	201-302-6

Quality Control

Our Tetramethylguanidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of industrial and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture and carbon dioxide, which can degrade product quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.468 - 1.472
Density (20°C)	0.918 - 0.922 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.