Description

Oxirane, 2-(4-Bromophenyl)-3-Methyl-, (2R,3S)- (9Ci) is a high-purity, chiral epoxide building block of significant interest in advanced organic synthesis. Its defined stereochemistry and reactive oxirane ring make it a critical intermediate for constructing complex, optically active molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require precise stereochemical control in their synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of novel, stereospecific herbicides, fungicides, and insecticides where the specific (2R,3S) configuration is crucial for bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialized polymers and epoxy resins with unique optical or mechanical properties derived from its aromatic bromine substituent.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening reactions and stereoselective transformations.

Basic Information

Product Name	Oxirane, 2-(4-Bromophenyl)-3-Methyl-, (2R,3S)- (9Ci)
CAS No.	797802-23-4
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	(2R,3S)-2-(4-Bromophenyl)-3-methyloxirane; trans-2-(4-Bromophenyl)-3-methyloxirane; 4-Bromo-α-methyl-trans-styrene oxide; (2R,3S)-3-Methyl-2-(4-bromophenyl)oxirane; 1,2-Epoxy-1-(4-bromophenyl)propane, (1R,2S)-rel-; (1R,2S)-1-(4-Bromophenyl)-1,2-epoxypropane; (2R,3S)-2-(p-Bromophenyl)-3-methyloxirane
EINECS	Contact for details

Quality Control

Our production of Oxirane, 2-(4-Bromophenyl)-3-Methyl-, (2R,3S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is fully characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. Under recommended storage conditions, the product is stable for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.