Description

Phenylacetic Acid-4-Boronic Acid Pinacol Ester is a high-value boronic ester derivative, a key building block in modern synthetic chemistry. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily utilized by research institutions and pharmaceutical companies in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced organic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for creating complex biaryl motifs found in many therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aromatic couplings.
• Material Science Research: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a stable, air-handleable boronic ester reagent for palladium-catalyzed carbon-carbon bond formation under mild conditions.
• Chemical Biology & Proteomics: Can be employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Industrial R&D: A versatile tool for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	Phenylacetic Acid-4-Boronic Acid Pinacol Ester
CAS No.	797755-07-8
Molecular Formula	C20H23BO4
Molecular Weight	338.21 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylacetic Acid; 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetic Acid; Phenylacetic Acid-4-Boronic Acid Pinacol Ester; 4-Carboxymethylphenylboronic Acid Pinacol Ester; (4-(Carboxymethyl)phenyl)boronic Acid Pinacol Ester; 797755-07-8; BRN 8512355
EINECS	Contact for details

Quality Control

Our Phenylacetic Acid-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.