Description

[2-(Ethoxycarbonyl)Pyridin-4-Yl]Boronic Acid is a high-purity boronic acid derivative and a versatile building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing pyridine and biphenyl motifs.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides through palladium-catalyzed coupling reactions.
• Material Science Research: Serves as a building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of novel bidentate ligands for transition metal catalysis.
• Chemical Biology Probes: Useful for synthesizing tagged molecules for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical reagent for CROs and CDMOs specializing in bespoke organic molecule production.

Basic Information

Product Name	[2-(Ethoxycarbonyl)Pyridin-4-Yl]Boronic Acid
CAS No.	794461-69-1
Molecular Formula	C9H12BNO4
Molecular Weight	209.01 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinic acid ethyl ester; Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate; Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylate; 2-Carbethoxy-4-pyridylboronic acid pinacol ester; (2-Ethoxycarbonylpyridin-4-yl)boronic acid pinacol ester; 4-Borono-2-ethoxycarbonylpyridine pinacol ester
EINECS	Contact for details

Quality Control

Our [2-(Ethoxycarbonyl)Pyridin-4-Yl]Boronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and potentially moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.