Description

2-(Bromomethyl)-1-Chloro-4-Iodobenzene is a versatile and highly functionalized halogenated aromatic building block. This compound is critical for advanced organic synthesis, particularly in the construction of complex molecules where precise halogen substitution patterns are required. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides where its halogen functionalities enable further derivatization.
• Material Science: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed reactions (e.g., Suzuki, Stille, Negishi) due to the presence of iodine and bromine leaving groups.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and organometallic catalysts used in homogeneous catalysis.

Basic Information

Product Name	2-(Bromomethyl)-1-Chloro-4-Iodobenzene
CAS No.	793695-85-9
Molecular Formula	C7H5BrClI
Molecular Weight	331.38 g/mol
Synonyms	1-Chloro-2-(bromomethyl)-4-iodobenzene; 4-Iodo-2-(bromomethyl)chlorobenzene; 2-Bromomethyl-1-chloro-4-iodobenzene; (2-Bromomethyl-4-iodophenyl)chloride; Benzene, 1-chloro-2-(bromomethyl)-4-iodo-; 793695-85-9; 1-Chloro-4-iodo-2-(bromomethyl)benzene
EINECS	Contact for details

Quality Control

Our 2-(Bromomethyl)-1-Chloro-4-Iodobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.