Description

1-Propanone,1-[(2R,3S)-2-Methyl-3-(2-Phenylethyl)Oxiranyl]-,Rel-(9Ci) CAS NO 791809-45-5 is a high-purity, chiral epoxide derivative of propanone, serving as a critical advanced intermediate in complex organic synthesis. Its defined stereochemistry makes it an invaluable building block for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily sought by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Serves as a versatile precursor in the manufacture of specialty chemicals, including flavors, fragrances, and advanced materials.
• Asymmetric Catalysis Research: Employed as a standard or substrate in academic and industrial research focused on developing new asymmetric synthesis methodologies.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	1-Propanone,1-[(2R,3S)-2-Methyl-3-(2-Phenylethyl)Oxiranyl]-,Rel-(9Ci)
CAS No.	791809-45-5
Molecular Formula	C14H18O2
Molecular Weight	218.29 g/mol
Synonyms	(2R,3S)-2-Methyl-3-(2-phenylethyl)oxiran-2-yl Ethanone; Rel-(2R,3S)-2-Methyl-3-(2-phenylethyl)oxiranyl Methyl Ketone; (R*,S*)-2-Methyl-3-(2-phenylethyl)oxirane-2-acetaldehyde (tautomer); 1-[(2R,3S)-2-Methyl-3-(2-phenylethyl)oxiranyl]ethanone; Chiral Epoxide Ketone Intermediate; 791809-45-5; (2R,3S)-Epoxide Propanone Derivative
EINECS	Contact for details

Quality Control

Our production of 1-Propanone,1-[(2R,3S)-2-Methyl-3-(2-Phenylethyl)Oxiranyl]-,Rel-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC-MS. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment. Our quality system is designed to support cGMP and ISO standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; therefore, containers should be kept sealed under an inert atmosphere when not in use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.