Description

Methyl 4-Hydroxy-2-(Trifluoromethyl)Benzoate is a high-value fluorinated aromatic ester building block. This compound matters for its unique trifluoromethyl and phenolic hydroxyl functional groups, which are critical for modulating the physicochemical properties of advanced molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, as well as by material scientists developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas like enzyme inhibitors and receptor modulators where the trifluoromethyl group enhances metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens, which are essential components in high-performance display technologies.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, enhancing properties such as chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis Building Block: A versatile reagent for constructing complex aromatic systems via ester hydrolysis, etherification, or cross-coupling reactions in fine chemical production.
• Chemical Research & Development: Utilized in academic and industrial labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	Methyl 4-Hydroxy-2-(Trifluoromethyl)Benzoate
CAS No.	790695-49-7
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	Methyl 2-(Trifluoromethyl)-4-hydroxybenzoate; 4-Hydroxy-2-(trifluoromethyl)benzoic Acid Methyl Ester; Benzoic acid, 4-hydroxy-2-(trifluoromethyl)-, methyl ester; Methyl 4-hydroxy-α,α,α-trifluoro-o-toluate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Hydroxy-2-(Trifluoromethyl)Benzoate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.