Description

2-Bromo-5-(Pyrrolidin-1-Ylsulfonyl)Benzoic Acid is a high-purity, functionalized benzoic acid derivative designed for advanced chemical synthesis. This compound serves as a critical sulfonamide-containing building block, offering a unique combination of a reactive bromo substituent and a pyrrolidine sulfonyl group for targeted molecular construction. It is primarily utilized by pharmaceutical and agrochemical R&D teams in the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition via sulfonamide pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the bromo and sulfonyl groups contribute to biological activity.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to the reactive bromine atom.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study protein-ligand interactions and biological pathways.
• Material Science Precursor: Can be used in the synthesis of specialized monomers or ligands for advanced polymers and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Bromo-5-(Pyrrolidin-1-Ylsulfonyl)Benzoic Acid
CAS No.	790272-15-0
Molecular Formula	C11H12BrNO4S
Molecular Weight	334.19 g/mol
Synonyms	2-Bromo-5-(1-pyrrolidinylsulfonyl)benzoic acid; Benzoic acid, 2-bromo-5-(1-pyrrolidinylsulfonyl)-; 5-(Pyrrolidine-1-sulfonyl)-2-bromobenzoic acid; 2-Bromo-5-(pyrrolidine-1-sulfonyl)benzoic acid; 790272-15-0; 2-Br-5-Pyrr-SO2-BA
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Pyrrolidin-1-Ylsulfonyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.