Description

4-(2-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Ethyl)-Morpholine is a high-value, synthetically versatile organoboron building block, essential for modern cross-coupling reactions. Its molecular architecture combines a protected boronic ester with a morpholine-substituted phenoxy linker, making it a critical intermediate for constructing complex molecules in pharmaceutical and advanced materials research. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex, bioactive molecules for next-generation herbicides, fungicides, and insecticides.
• Material Science & OLED Development: Serves as a building block for creating organic semiconductors, light-emitting materials, and charge-transport layers in electronic devices.
• Ligand & Catalyst Design: The morpholine and boronate functional groups make it useful for developing novel ligands and catalysts for asymmetric synthesis.
• Polymer Chemistry: Incorporated into polymer backbones to introduce specific functionality, solubility, or self-assembly properties.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	4-(2-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Ethyl)-Morpholine
CAS No.	787591-39-3
Molecular Formula	C18H28BNO4
Molecular Weight	333.23 g/mol
Synonyms	2-[4-[2-(4-Morpholinyl)ethoxy]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)morpholine; Morpholine, 4-[2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]ethyl]-; 4-(2-(4-(Pinacolatoboryl)phenoxy)ethyl)morpholine; B-[4-[2-(4-Morpholinyl)ethoxy]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of 4-(2-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Ethyl)-Morpholine is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles via validated methods such as HPLC, NMR, and GC.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.