Description

4-Fluoromethylpiperidine Hydrochloride is a high-purity, functionalized piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active ingredients. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate fluorinated piperidine motifs into their molecular designs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the fluoromethylpiperidine moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the design of molecular probes due to its fluorine atom, which can be used as a spectroscopic label.
• Material Science Precursor: Potential monomer or functional additive in the synthesis of specialty polymers and advanced materials.

Basic Information

Product Name	4-Fluoromethylpiperidine Hydrochloride
CAS No.	787564-27-6
Molecular Formula	C6H13ClFN
Molecular Weight	153.63 g/mol
Synonyms	4-(Fluoromethyl)piperidine hydrochloride; 4-Fluoromethyl-piperidine HCl; Piperidine, 4-(fluoromethyl)-, hydrochloride; 1-(Fluoromethyl)piperidin-4-amine hydrochloride (tautomer); 4-Fluoropiperidinemethane hydrochloride; FC-687 (potential research code); 787564-27-6 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4-Fluoromethylpiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide full traceability and Certificates of Analysis (COA) with every shipment, detailing assay, impurity profiles, and physical characteristics to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.