Description

m-Peg4-Sulfonic Acid CAS NO 787524-78-1 is a high-purity, functionalized polyethylene glycol derivative featuring a terminal sulfonic acid group, making it a valuable bifunctional linker and building block. This compound is essential for introducing hydrophilic, anionic, and reactive properties into target molecules, enabling precise chemical modifications. It is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science industries for developing advanced drug delivery systems, functional polymers, and diagnostic reagents.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of antibody-drug conjugates (ADCs), prodrugs, and targeted therapeutics.
• Bioconjugation & Linker Chemistry: Used to attach drugs, dyes, or other payloads to proteins, peptides, or nanoparticles via its reactive PEG spacer and sulfonic acid group.
• Polymer Modification: Imparts hydrophilicity and ionic character to polymers for creating specialized hydrogels, coatings, and functional materials.
• Surface Functionalization: Employed to modify surfaces with sulfonate groups to enhance biocompatibility, reduce non-specific binding, or introduce specific chemical reactivity.
• Catalyst & Ligand Synthesis: Serves as a precursor for creating water-soluble ligands and catalysts for green chemistry applications.
• Diagnostic Reagent Development: Utilized in the design of contrast agents, biosensors, and other diagnostic tools requiring solubility and functional handles.

Basic Information

Item	Details
Product Name	m-Peg4-Sulfonic Acid
CAS No.	787524-78-1
Molecular Formula	C13H28O9S
Molecular Weight	360.42 g/mol
Synonyms	1-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethylsulfonic acid; 3,6,9,12-Tetraoxapentadecane-1-sulfonic acid, 15-methoxy-; mPEG4-sulfonic acid; Methoxy-PEG4-sulfonic acid; PEG4 methyl ether sulfonic acid; 15-Methoxy-3,6,9,12-tetraoxapentadecane-1-sulfonic acid; 2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethanesulfonic acid
EINECS	Contact for details

Quality Control

Our m-Peg4-Sulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.