Description

1H-Dibenz[B,E]Azepine,2,3,4,4A,5,6,11,11A-Octahydro-5-Methyl-(9Ci) is a complex, polycyclic organic compound belonging to the dibenzazepine class, serving as a valuable advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. Its intricate fused-ring structure makes it a critical precursor for the research and development of novel active pharmaceutical ingredients (APIs), particularly in the fields of central nervous system (CNS) and neurological therapeutics. This high-purity intermediate is essential for pharmaceutical R&D laboratories, fine chemical synthesis units, and contract manufacturing organizations (CMOs) seeking reliable, high-quality raw materials for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel dibenzazepine-based drug candidates and active pharmaceutical ingredients (APIs).
• Neurological & CNS Drug Research: Used in the development of potential therapeutic agents targeting neurological disorders, psychiatric conditions, and pain management.
• Medicinal Chemistry & Lead Optimization: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and the generation of compound libraries for high-throughput screening.
• Fine Chemical Synthesis: Employed in academic and industrial research for constructing complex polycyclic molecular architectures.
• Contract Manufacturing: Supplied to CMOs and CDMOs for use in custom synthesis projects and the scale-up of proprietary chemical processes.

Basic Information

Product Name	1H-Dibenz[B,E]Azepine,2,3,4,4A,5,6,11,11A-Octahydro-5-Methyl-(9Ci)
CAS No.	785719-65-5
Molecular Formula	C15H19N
Molecular Weight	213.32 g/mol
Synonyms	5-Methyl-2,3,4,4a,5,6,11,11a-octahydro-1H-dibenz[b,e]azepine; Octahydro-5-methyl-1H-dibenz[b,e]azepine; 1H-Dibenz[b,e]azepine, 2,3,4,4a,5,6,11,11a-octahydro-5-methyl-; 5-Methyloctahydro-1H-dibenz[b,e]azepine; 785719-65-5; Dibenzazepine derivative
EINECS	Contact for details

Quality Control

Our 1H-Dibenz[B,E]Azepine derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.