Description

Cyclohexanone, 3-[(1E)-2-(2-Methylphenyl)Ethenyl]-, (3S)- (9Ci) is a chiral, substituted cyclohexanone derivative featuring a conjugated (E)-stilbene-like moiety. This specific stereochemistry and structural framework make it a valuable advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of complex, optically active molecules. The compound, identified by CAS No. 783370-40-1, is critical for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, anti-inflammatory agents, or other therapeutic areas.
• Asymmetric Synthesis: Serves as a sophisticated chiral synthon for constructing complex natural products and bioactive compounds via stereoselective reactions.
• Ligand and Catalyst Development: Utilized in the research and development of novel chiral ligands and organocatalysts for enantioselective transformations.
• Material Science Research: Potential monomer or precursor for developing specialty polymers with unique optical or electronic properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in regulatory submissions.
• Academic & Industrial R&D: Employed in exploratory chemistry for drug discovery programs and the development of new synthetic methodologies.

Basic Information

Product Name	Cyclohexanone, 3-[(1E)-2-(2-Methylphenyl)Ethenyl]-, (3S)- (9Ci)
CAS No.	783370-40-1
Molecular Formula	C15H18O
Molecular Weight	214.30 g/mol
Synonyms	(3S)-3-[(1E)-2-(2-Methylphenyl)ethenyl]cyclohexan-1-one; (S)-3-[(E)-2-(o-Tolyl)vinyl]cyclohexanone; (3S)-3-[(E)-2-(2-Methylphenyl)vinyl]cyclohexanone; (S)-3-(2-(2-Methylphenyl)vinyl)cyclohexanone (E-isomer); (S)-3-[(E)-2-(o-Methylstyryl)]cyclohexanone; Chiral o-Methylstilbene Cyclohexanone Derivative; (S)-Enantiomer of CAS 783370-40-1
EINECS	Contact for details

Quality Control

We supply Cyclohexanone, 3-[(1E)-2-(2-Methylphenyl)Ethenyl]-, (3S)- (9Ci) under a stringent quality management system. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) is provided, detailing results for chiral purity (HPLC), chemical purity (GC/HPLC), structural confirmation (NMR, IR), and other relevant parameters. Our quality commitment supports your regulatory and intellectual property requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee (by Chiral HPLC)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.