Description

2-Buten-1-Amine,3-(4-Fluorophenyl)-,(E)-(9Ci) is a specialized fluorinated amine building block with significant utility in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the (E)-configuration and fluorophenyl moiety are critical for biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom enhances bioavailability and metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Acts as a precursor for the manufacture of other high-value, fluorinated specialty chemicals and dyes.
• Academic and R&D: Utilized in university and institutional research for methodological studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	2-Buten-1-Amine,3-(4-Fluorophenyl)-,(E)-(9Ci)
CAS No.	783275-26-3
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	(E)-3-(4-Fluorophenyl)but-2-en-1-amine; (E)-3-(p-Fluorophenyl)-2-buten-1-amine; trans-3-(4-Fluorophenyl)-2-buten-1-amine; 3-(4-Fluorophenyl)-2-buten-1-amine, (E)-; 2-Buten-1-amine, 3-(4-fluorophenyl)-, (E)-; 783275-26-3; (E)-1-Amino-3-(4-fluorophenyl)-2-butene
EINECS	Contact for details

Quality Control

Our 2-Buten-1-Amine,3-(4-Fluorophenyl)-,(E)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (E-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.