Description

Diazene, Hydroxy(1-Phenylethyl)-, [R-(E)]- (9Ci) is a specialized chiral diazene derivative, a key intermediate in the synthesis of optically active compounds. Its value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in the development of pharmaceuticals and advanced materials. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific stereochemistry into their target molecules. The compound is supplied under controlled conditions to ensure its chemical integrity and performance in sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in asymmetric synthesis.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Manufacturing: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic and Industrial R&D: A valuable tool for methodological development in organic chemistry, enabling studies in radical chemistry and nitrogen transfer reactions.
• Material Science Research: Investigated as a potential monomer or cross-linking agent for creating polymers with unique optical or electronic properties.

Basic Information

Product Name	Diazene, Hydroxy(1-Phenylethyl)-, [R-(E)]- (9Ci)
CAS No.	783275-09-2
Molecular Formula	C8H10N2O
Molecular Weight	150.18 g/mol
Synonyms	(R,E)-1-Phenylethylhydroxydiazene; (R)-N-Hydroxy-1-phenylethanimine; (R,E)-α-Methylbenzaldehyde oxime N-oxide; (1R)-N-Hydroxy-1-phenylethanimine; Hydroxy[(1R)-1-phenylethyl]diazene; [R-(E)]-Hydroxy(1-phenylethyl)diazene; A chiral diazene N-oxide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Diazene, Hydroxy(1-Phenylethyl)-, [R-(E)]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure identity, strength, and chemical purity meet exacting standards. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess, and related substances are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in darkness. For long-term storage, consider under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.