Description

L-Serine, o-[(2-Methylphenyl)Methyl]- (9Ci) is a specialized, non-proteinogenic serine derivative characterized by a benzyl-type substitution at the hydroxyl group. This structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for creating complex molecules with specific stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals. The compound, identified by CAS NO 782448-82-2, offers a precise handle for introducing serine-like motifs into target structures under controlled conditions.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, including protease inhibitors and receptor modulators.
• Peptidomimetic Chemistry: Used to construct modified peptide backbones where the side chain properties of serine are required but with enhanced stability or altered lipophilicity.
• Chemical Biology Research: Employed as a tool compound or building block for synthesizing probes to study enzyme mechanisms or protein-protein interactions.
• Asymmetric Synthesis: Acts as a starting material or auxiliary in catalytic asymmetric reactions to generate enantiomerically pure compounds.
• Ligand and Catalyst Development: Provides a scaffold for creating novel chelating ligands or organocatalysts used in synthetic chemistry.

Basic Information

Product Name	L-Serine, o-[(2-Methylphenyl)Methyl]- (9Ci)
CAS No.	782448-82-2
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	O-(2-Methylbenzyl)-L-serine; (S)-2-Amino-3-[(2-methylphenyl)methoxy]propanoic acid; L-Serine, O-[(2-methylphenyl)methyl]-; Serine, O-(2-methylbenzyl)-, L-; 782448-82-2; (S)-3-((2-Methylbenzyl)oxy)-2-aminopropanoic acid
EINECS	Contact for details

Quality Control

Our production of L-Serine, o-[(2-Methylphenyl)Methyl]- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.5%
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.