Description

4-(n-Boc-n-Methylamino)-Benzaldehyde CAS NO 780821-17-2 is a high-purity, protected amino aldehyde building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other small molecule therapeutics.
• Peptidomimetic Synthesis: Used to introduce protected amino-benzaldehyde motifs into peptide chains, enabling the creation of novel peptidomimetics and constrained peptides.
• Linker Chemistry: Serves as a versatile starting material for constructing specialized linkers used in PROTACs (Proteolysis Targeting Chimeras) and antibody-drug conjugates (ADCs).
• Agrochemical Research: Employed in the discovery and development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a monomer or functionalization agent in the synthesis of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological pathways and target engagement.

Basic Information

Product Name	4-(n-Boc-n-Methylamino)-Benzaldehyde
CAS No.	780821-17-2
Molecular Formula	C14H19NO3
Molecular Weight	249.31 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)(methyl)amino]benzaldehyde; 4-[(tert-Butoxycarbonyl)(methyl)amino]benzenecarboxaldehyde; 4-(N-Boc-N-methylamino)benzaldehyde; 4-(N-Methyl-N-Boc-amino)benzaldehyde; p-(N-Boc-N-methylamino)benzaldehyde; 4-[(1,1-Dimethylethoxy)carbonyl(methyl)amino]benzaldehyde; 4-(tert-Butoxycarbonyl(methyl)amino)benzaldehyde; Boc-N-Me-4-Aminobenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-(n-Boc-n-Methylamino)-Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.