Description

2-Pyridinecarboxaldehyde, 3,5-Difluoro- (9Ci) is a versatile fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the strategic positioning of fluorine atoms on the pyridine ring, which significantly influences the electronic properties and metabolic stability of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized nitrogen-containing ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of novel fluorinated polymers, liquid crystals, and electronic materials that require specific electronic and steric properties.
• Chemical Biology Probe Development: Utilized to create fluorescent tags, cross-linking agents, and other molecular probes for studying biological systems.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and academic laboratories engaged in medicinal chemistry and novel synthetic route exploration.

Basic Information

Item	Detail
Product Name	2-Pyridinecarboxaldehyde, 3,5-Difluoro- (9Ci)
CAS No.	780801-58-3
Molecular Formula	C6H3F2NO
Molecular Weight	143.09 g/mol
Synonyms	3,5-Difluoropyridine-2-carboxaldehyde; 3,5-Difluoro-2-formylpyridine; 3,5-Difluoro-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 3,5-difluoro-; 3,5-Difluoropicolinaldehyde; 2-Formyl-3,5-difluoropyridine; 3,5-Difluoro-2-pyridylcarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxaldehyde, 3,5-Difluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.