Description

Threo-Hex-4-Enonic Acid, 2-Amino-3,6-Anhydro-2,4,5-Trideoxy-4-Methyl- (9Ci) is a specialized chiral building block and advanced pharmaceutical intermediate of significant interest in synthetic organic chemistry. Its complex, functionalized structure makes it a valuable precursor for the development of novel bioactive molecules, particularly in carbohydrate-based drug discovery. This high-purity compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors who require precise, high-quality intermediates for complex synthesis.

Application

This advanced chemical intermediate serves critical roles in sophisticated research and manufacturing processes. Key application areas include:

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel nucleoside analogs, antiviral agents, and other carbohydrate-based therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for probing carbohydrate-processing pathways.
• Glycochemistry: Serves as a building block for the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics with potential therapeutic applications.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs targeting infectious diseases or metabolic disorders.
• Process Chemistry Development: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) that incorporate modified sugar moieties.

Basic Information

Product Name	Threo-Hex-4-Enonic Acid, 2-Amino-3,6-Anhydro-2,4,5-Trideoxy-4-Methyl- (9Ci)
CAS No.	780750-23-4
Molecular Formula	C7H11NO4
Molecular Weight	173.17 g/mol
Synonyms	2-Amino-3,6-anhydro-2,4,5-trideoxy-4-methyl-D-threo-hex-4-enonic acid; 4-Methyl-2-amino-3,6-anhydro-2,4,5-trideoxy-D-threo-hex-4-enonic acid; (2R,3S)-2-Amino-3,6-anhydro-2,4,5-trideoxy-4-methylhex-4-enonic acid; D-threo-Hex-4-enonic acid, 2-amino-3,6-anhydro-2,4,5-trideoxy-4-methyl-; A potential intermediate for Carbocyclic nucleoside synthesis.
EINECS	Contact for details

Quality Control

Our production of Threo-Hex-4-Enonic Acid, 2-Amino-3,6-Anhydro-2,4,5-Trideoxy-4-Methyl- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.