Description

1-Naphthalenol,1,2,3,4,4A,5,6,7-Octahydro-3,3,5,8-Tetramethyl-,(1R,4Ar,5S)-Rel-(9Ci) is a high-purity, stereochemically defined octahydronaphthalenol derivative that serves as a critical chiral intermediate in advanced organic synthesis. This compound matters for its precise molecular architecture, which is essential for constructing complex molecules with specific spatial orientations, a key requirement in modern pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and fragrance industries for applications requiring high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing complex, stereospecific odorants and flavor compounds in high-value perfumery.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals where the rigid, fused-ring structure imparts desired material properties.
• Catalyst & Ligand Development: Acts as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Item	Detail
Product Name	1-Naphthalenol,1,2,3,4,4A,5,6,7-Octahydro-3,3,5,8-Tetramethyl-,(1R,4Ar,5S)-Rel-(9Ci)
CAS No.	776295-18-2
Molecular Formula	C₁₄H₂₄O
Molecular Weight	208.34 g/mol
Synonyms	(1R,4aR,5S)-1,2,3,4,4a,5,6,7-Octahydro-3,3,5,8-tetramethyl-1-naphthalenol; 1-Naphthalenol, 1,2,3,4,4a,5,6,7-octahydro-3,3,5,8-tetramethyl-, (1R,4aR,5S)-rel-; Octahydro-3,3,5,8-tetramethyl-1-naphthalenol (relative stereochemistry); Chiral Octahydronaphthalenol Derivative; Tetramethyloctahydronaphthalenol
EINECS	Contact for details

Quality Control

Our 1-Naphthalenol,1,2,3,4,4A,5,6,7-Octahydro-3,3,5,8-Tetramethyl-,(1R,4Ar,5S)-Rel-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and structural confirmation by NMR and IR spectroscopy, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with full specification data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; keep container tightly sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.