Description

Benzamide, n-(2-Cyanoethyl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a specialized boronic ester derivative of benzamide, serving as a crucial synthetic intermediate in modern organic chemistry. Its value lies in the combination of a protected boronic acid group and a cyanoethyl-substituted amide moiety, enabling precise cross-coupling reactions and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors developing novel active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring Suzuki-Miyaura cross-coupling reactions to form biaryl structures.
• Agrochemical Research: Used in the development of new herbicides and pesticides where the boronic ester group allows for efficient structural diversification.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or host materials in the fabrication of advanced display and lighting technologies.
• Ligand Synthesis for Catalysis: The amide and boronate functional groups can be utilized to create novel ligands for transition metal catalysts.
• Polymer Chemistry: Acts as a monomer or functionalization agent in the synthesis of specialty polymers with tailored electronic or mechanical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes, leveraging its potential for bioconjugation.

Basic Information

Product Name	Benzamide, n-(2-Cyanoethyl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	775351-59-2
Molecular Formula	C₁₆H₂₁BN₂O₃
Molecular Weight	300.16 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(2-cyanoethyl)benzamide; N-(2-Cyanoethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 3-Pinacolatoboryl-N-(2-cyanoethyl)benzamide; Benzamide, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(2-cyanoethyl)-; (3-((2-Cyanoethyl)carbamoyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Benzamide, n-(2-Cyanoethyl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.