Description

(2-(2H-Tetrazol-5-Yl)Phenyl)Boronic Acid Pinacol Ester is a specialized boronic acid ester derivative that serves as a crucial synthetic intermediate. Its value lies in its dual functionality, combining the tetrazole heterocycle, a common bioisostere for carboxylic acids, with the versatile boronic ester group used in cross-coupling reactions. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the synthesis of drug candidates where the tetrazole moiety acts as a metabolically stable carboxylic acid bioisostere.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-tetrazole motifs.
• Material Science: Precursor for creating functionalized polymers or metal-organic frameworks (MOFs) with specific ligand properties.
• Chemical Biology Probes: Synthesis of tagged molecules for studying biological pathways and protein interactions.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	(2-(2H-Tetrazol-5-Yl)Phenyl)Boronic Acid Pinacol Ester
CAS No.	775351-35-4
Molecular Formula	C₁₃H₁₇BN₄O₂
Molecular Weight	272.11 g/mol
Synonyms	5-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-tetrazole; 2-(2H-Tetrazol-5-yl)benzeneboronic acid pinacol ester; (2-(1H-Tetrazol-5-yl)phenyl)boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyltetrazole; B-(2-(1H-Tetrazol-5-yl)phenyl)boronic acid pinacol ester; Tetrazole-phenylboronic ester; 775351-35-4; Boronic acid, B-[2-(1H-tetrazol-5-yl)phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (2-(2H-Tetrazol-5-Yl)Phenyl)Boronic Acid Pinacol Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.