Description

4-Bromo-1-Chloro-2-Iodobenzene is a highly functionalized halogenated benzene derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique combination of three distinct halogen substituents on a single aromatic ring makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of functionalized ligands.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where halogenated aromatic cores are required for bioactivity.
• Material Science & OLED Development: Serves as a building block for creating complex organic semiconductors, liquid crystals, and light-emitting materials for electronic devices.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized phosphine ligands and metal-organic frameworks (MOFs) due to its ability to introduce multiple functional handles.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and constructing molecular libraries.

Basic Information

Product Name	4-Bromo-1-Chloro-2-Iodobenzene
CAS No.	774608-49-0
Molecular Formula	C6H3BrClI
Molecular Weight	317.35 g/mol
Synonyms	1-Bromo-4-Chloro-2-Iodobenzene; 2-Iodo-4-Bromochlorobenzene; 4-Bromo-2-Iodochlorobenzene; 2-Iodo-1-Chloro-4-Bromobenzene; Benzene, 1-bromo-4-chloro-2-iodo-; 4-Bromo-1-chloro-2-iodo-Benzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Chloro-2-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling and storage should minimize exposure to light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.