Description

Bicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid, 2-Amino-, [1R-(Exo,Exo)]- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid norbornane skeleton and strategically positioned amino and dicarboxylic acid functional groups make it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), catalysts, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Catalyst & Ligand Development: Serves as a core structure for designing novel asymmetric catalysts and chiral ligands used in enantioselective synthesis.
• Advanced Material Science: Used in the research and development of specialty polymers, resins, and dendrimers with tailored thermal and mechanical properties.
• Agrochemical Research: Employed as a building block for creating novel, stereospecific active ingredients for crop protection products.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and the exploration of new chemical spaces.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid, 2-Amino-, [1R-(Exo,Exo)]- (9Ci)
CAS No.	774516-60-8
Molecular Formula	C9H13NO4
Molecular Weight	199.20 g/mol
Synonyms	(1R,2R,3S,4S)-3-Aminobicyclo[2.2.1]heptane-2,3-dicarboxylic acid; 2-Aminonorbornane-2,3-dicarboxylic acid (endo,endo isomer); exo-2-Aminobicyclo[2.2.1]heptane-2,3-dicarboxylic acid; (1R,2R,3S,4S)-3-Amino-2,3-norbornanedicarboxylic acid; Chiral Norbornane Amino Diacid; (1R)-exo,exo-2-Amino-2,3-norbornanedicarboxylic acid
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid, 2-Amino-, [1R-(Exo,Exo)]- (9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure consistent identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider refrigeration (2-8°C) under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.