Description

2-Piperazinecarboxaldehyde CAS NO 773866-77-6 is a versatile and highly functionalized heterocyclic building block, serving as a critical intermediate in advanced organic synthesis. Its value lies in the reactive aldehyde group, which enables the construction of complex molecular architectures through condensation, reductive amination, and other key transformations. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who are developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of piperazine-based drug candidates, including potential treatments for central nervous system disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the piperazine scaffold imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: Incorporated into monomers and functional additives to modify polymer properties such as thermal stability and solubility.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and constructing heterocyclic libraries for screening.
• Custom Synthesis Building Block: Provided for contract research and manufacturing organizations (CROs/CMOs) requiring high-purity, specialized intermediates for client projects.

Basic Information

Product Name	2-Piperazinecarboxaldehyde
CAS No.	773866-77-6
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	Piperazine-2-carboxaldehyde; 2-Formylpiperazine; 2-Piperazinecarbaldehyde; Piperazine-2-carbaldehyde; 1-Piperazinecarboxaldehyde; 2-Carboxaldehydepiperazine; 2-Piperazinylmethanal; 1,4-Diazacyclohexane-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Piperazinecarboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.