Description

Ethyl 4-Chloro-2,6-Difluorobenzoate is a high-purity fluorinated benzoate ester derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for R&D chemists and production specialists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing difluorobenzene motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the chloro-difluoro substitution pattern enhances biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to introduce functionalized benzoate groups.
• Polymer Chemistry Modifier: Acts as a monomer or modifier for creating specialty polymers with specific thermal or chemical resistance properties.
• Chemical Research & Development: A valuable tool for academic and industrial research labs exploring new fluorination chemistry and reaction pathways.

Basic Information

Product Name	Ethyl 4-Chloro-2,6-Difluorobenzoate
CAS No.	773139-38-1
Molecular Formula	C9H7ClF2O2
Molecular Weight	220.60 g/mol
Synonyms	Benzoic acid, 4-chloro-2,6-difluoro-, ethyl ester; Ethyl 4-chloro-2,6-difluorobenzoate; 4-Chloro-2,6-difluorobenzoic acid ethyl ester; 2,6-Difluoro-4-chlorobenzoic acid ethyl ester; Ethyl 4-chloro-2,6-difluorobenzoate; Ethyl 4-chloro-α,α-difluorobenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-2,6-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring a reliable supply for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.