Description

Ethyl 2,3-Difluorobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. This compound is valued for its role in introducing the 2,3-difluorophenyl moiety, a key structural feature that can modulate the biological activity and physicochemical properties of target molecules. It is primarily sought by R&D and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluorobenzene unit enhances stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated components for electronic display materials, contributing to improved performance and stability.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate for developing novel synthetic methodologies in academic and industrial research.
• Fluorinated Polymer Modifiers: Acts as a monomer or modifier in the synthesis of specialty polymers to impart specific chemical resistance or surface properties.

Basic Information

Product Name	Ethyl 2,3-Difluorobenzoate
CAS No.	773134-65-9
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	2,3-Difluorobenzoic Acid Ethyl Ester; Ethyl 2,3-Difluorobenzoate; Benzoic acid, 2,3-difluoro-, ethyl ester; 2,3-Difluorobenzoic Acid Ethyl Ester; Ethyl 2,3-difluorobenzoate; 773134-65-9; Ethyl o,m-difluorobenzoate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2,3-Difluorobenzoate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency. Our quality commitment includes providing comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.