Description

(2E)-3-[6-(Trifluoromethyl)Pyridin-3-Yl]Propenoic Acid is a high-value trifluoromethylpyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique combination of the pyridine heterocycle and the trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients. The CAS number for this compound is 773131-93-4.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of modern pesticides, herbicides, and fungicides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors, due to its electron-withdrawing characteristics.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(2E)-3-[6-(Trifluoromethyl)Pyridin-3-Yl]Propenoic Acid
CAS No.	773131-93-4
Molecular Formula	C9H6F3NO2
Molecular Weight	217.15 g/mol
Synonyms	(E)-3-(6-(Trifluoromethyl)pyridin-3-yl)acrylic acid; trans-3-[6-(Trifluoromethyl)-3-pyridyl]acrylic acid; 3-(6-(Trifluoromethyl)pyridin-3-yl)-2-propenoic acid; 773131-93-4; (2E)-3-[6-(Trifluoromethyl)-3-pyridinyl]-2-propenoic acid
EINECS	Contact for details

Quality Control

Our (2E)-3-[6-(Trifluoromethyl)Pyridin-3-Yl]Propenoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports your R&D and production needs with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.