Description

4-Methoxy-2-(Trifluoromethyl)Cinnamicacid CAS NO 773131-66-1 is a specialized fluorinated cinnamic acid derivative, serving as a high-value synthetic intermediate. Its molecular structure, featuring both a methoxy group and a trifluoromethyl substituent, makes it a critical building block for creating advanced molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors seeking to incorporate fluorinated aromatic motifs into new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for anti-inflammatory and oncology research, leveraging the metabolic stability imparted by the trifluoromethyl group.
• Agrochemical Synthesis: Used in developing next-generation herbicides and fungicides, where the fluorinated aromatic core enhances bioavailability and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, where its rigid, substituted cinnamate structure contributes to desired optical and electronic properties.
• Organic Synthesis & Catalysis Research: A valuable substrate for methodological studies in cross-coupling reactions and the development of new fluorination techniques.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes, benefiting from the distinct spectroscopic signature of the fluorinated moiety.

Basic Information

Product Name	4-Methoxy-2-(Trifluoromethyl)Cinnamicacid
CAS No.	773131-66-1
Molecular Formula	C₁₁H₉F₃O₃
Molecular Weight	246.18 g/mol
Synonyms	(E)-3-[4-Methoxy-2-(trifluoromethyl)phenyl]acrylic acid; 4-Methoxy-2-(trifluoromethyl)cinnamic acid; 2-Trifluoromethyl-4-methoxycinnamic acid; (E)-3-(4-Methoxy-2-(trifluoromethyl)phenyl)-2-propenoic acid; 4-Methoxy-α-methyl-2-(trifluoromethyl)cinnamic acid (related isomer); 773131-66-1; 4-Methoxy-2-trifluoromethylcinnamic acid
EINECS	Contact for details

Quality Control

Our production of 4-Methoxy-2-(Trifluoromethyl)Cinnamicacid adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity confirmation, and impurity profiles. For projects requiring specific regulatory support, we can discuss compliance with relevant quality frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.