Description

2-(2-Bromo-4-Fluorophenyl)-1,3-Dioxolane is a high-value, multi-functional chemical intermediate characterized by its bromo- and fluoro-substituted aromatic ring protected by a dioxolane group. This compound matters for its role in facilitating complex synthetic pathways, particularly in the development of advanced pharmaceutical and agrochemical actives where precise halogen substitution is critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the reactivity of the bromine atom for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of novel organic electronic materials and liquid crystals due to its stable, substituted aromatic core.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and Industrial R&D: Fundamental research tool in organic chemistry for studying protection/deprotection strategies and cross-coupling reactions.

Basic Information

Item	Details
Product Name	2-(2-Bromo-4-Fluorophenyl)-1,3-Dioxolane
CAS No.	773097-04-4
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	2-(2-Bromo-4-fluorophenyl)-1,3-dioxolane; 1,3-Dioxolane, 2-(2-bromo-4-fluorophenyl)-; 2-Bromo-4-fluorobenzaldehyde ethylene acetal; (2-Bromo-4-fluorophenyl)-1,3-dioxolane; 2-(2-Bromo-4-fluorophenyl)-[1,3]dioxolane; Benzaldehyde, 2-bromo-4-fluoro-, ethylene acetal; 2-Bromo-4-fluoro-1,3-benzodioxole (common misnomer, refers to a different structure); 4-Fluoro-2-bromobenzaldehyde ethylene acetal
EINECS	Contact for details

Quality Control

Our 2-(2-Bromo-4-Fluorophenyl)-1,3-Dioxolane is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.