Description

(2-Methyl-4-(Trifluoromethoxy)Phenyl)Methanamine is a high-value aromatic amine building block featuring a trifluoromethoxy substituent, which imparts unique electronic and steric properties. This compound is essential for medicinal chemistry and agrochemical research, where it serves as a critical intermediate for introducing lipophilic and metabolically stable motifs into target molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and crop protection industries for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and fluorescent tags to study biological systems and enzyme mechanisms.

Basic Information

Product Name	(2-Methyl-4-(Trifluoromethoxy)Phenyl)Methanamine
CAS No.	771572-39-5
Molecular Formula	C9H10F3NO
Molecular Weight	205.18 g/mol
Synonyms	1-[2-Methyl-4-(trifluoromethoxy)phenyl]methanamine; 2-Methyl-4-(trifluoromethoxy)benzylamine; α-Methyl-4-(trifluoromethoxy)benzylamine; (2-Methyl-4-(trifluoromethoxyphenyl))methylamine; 4-(Trifluoromethoxy)-2-methylbenzylamine; 2-Methyl-α-(trifluoromethoxy)benzylamine; Benzenemethanamine, 2-methyl-4-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our (2-Methyl-4-(Trifluoromethoxy)Phenyl)Methanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This amine is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.