Description

Propanedinitrile, [(7-Methyl-1H-Indol-3-Yl)Methyl]- (9Ci) is a specialized organic building block featuring a malononitrile moiety linked to a substituted indole scaffold. This molecular architecture makes it a valuable intermediate for synthesizing complex heterocyclic compounds and functional materials. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical sectors for lead optimization and the creation of novel active ingredients. Its unique structure also presents opportunities in materials science for the development of advanced organic electronic components.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system disorders and oncological pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Organic Synthesis Building Block: The reactive malononitrile group enables its use in Knoevenagel condensations and cyclization reactions to construct complex heterocycles.
• Materials Science Precursor: Investigated for the preparation of organic semiconductors, non-linear optical (NLO) materials, and metal-organic frameworks (MOFs).
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding.

Basic Information

Item	Detail
Product Name	Propanedinitrile, [(7-Methyl-1H-Indol-3-Yl)Methyl]- (9Ci)
CAS No.	771526-87-5
Molecular Formula	C13H11N3
Molecular Weight	209.25 g/mol
Synonyms	(7-Methyl-1H-indol-3-yl)methylpropanedinitrile; 2-[(7-Methyl-1H-indol-3-yl)methyl]malononitrile; 3-(Malononitrilomethyl)-7-methylindole; [(7-Methyl-1H-indol-3-yl)methyl]propanedinitrile; 7-Methyl-3-indolylmethylmalononitrile; Malononitrile, [(7-methyl-1H-indol-3-yl)methyl]-
EINECS	Contact for details

Quality Control

Every batch of Propanedinitrile, [(7-Methyl-1H-Indol-3-Yl)Methyl]- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting the specific results for your batch. Our quality systems are designed to support cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere or with desiccant for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.