Description

(-)-6Beta-Hydroxy-5Beta,8Beta,9Beta,10Alpha-Cleroda-3,13-Dien-16,15-Olid-18-Oic Acid is a high-purity, structurally defined clerodane diterpenoid compound. This specialized natural product derivative is valued for its role as a critical reference standard and a key pharmaceutical intermediate in advanced research and development. It is primarily sought by organizations in the pharmaceutical, biotechnology, and phytochemical research sectors for applications in drug discovery and analytical method development.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of clerodane diterpenoids in complex matrices via HPLC, LC-MS, and NMR.
• Drug Discovery Intermediate: Serves as a sophisticated building block for the semi-synthesis of novel therapeutic agents targeting inflammation, pain, and infectious diseases.
• Natural Product Research: Acts as a crucial analytical marker in the study of medicinal plants from the *Clerodendrum* and related genera, facilitating standardization of extracts.
• Bioactivity Screening: Employed in high-throughput assays to evaluate specific biological activities, including anti-inflammatory, antimicrobial, and cytotoxic effects.
• Metabolite Synthesis: Utilized in the preparation of potential human or microbial metabolites for pharmacokinetic and toxicology studies.
• Academic & Contract Research: Essential for universities and CROs conducting fundamental research on diterpenoid chemistry and biosynthesis.

Basic Information

Product Name	(-)-6Beta-Hydroxy-5Beta,8Beta,9Beta,10Alpha-Cleroda-3,13-Dien-16,15-Olid-18-Oic Acid
CAS No.	771493-42-6
Molecular Formula	C20H26O5
Molecular Weight	346.42 g/mol
Synonyms	(-)-6β-Hydroxy-5β,8β,9β,10α-Cleroda-3,13-dien-16,15-olide-18-oic Acid; 16,15-Olid-18-oic Acid Derivative; Clerodane Diterpenoid Acid; 6β-Hydroxycleroda-3,13-dien-16,15-olide-18-oic Acid; (5β,8β,9β,10α)-6β-Hydroxycleroda-3,13-dien-16,15-olide-18-oic Acid; Cleroda-3,13-dien-16,15-olide-18-oic Acid, 6β-hydroxy-; CAS 771493-42-6
EINECS	Contact for details

Quality Control

Our (-)-6Beta-Hydroxy-5Beta,8Beta,9Beta,10Alpha-Cleroda-3,13-Dien-16,15-Olid-18-Oic Acid is produced under a strict quality management system. Each batch is subjected to comprehensive analytical characterization, including HPLC for purity, and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and relevant analytical data.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.