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((2S,3R)-4-(4-Chloro-1,1,2,2,3,3,4,4-Octafluorobutylsulfonyl)-3-(2-Chlorophenyl)-5-Phenyl-2,3-Dihydrofuran-2-Yl)(Phenyl)Methanone CAS NO 771491-59-9
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CAS No.:771491-59-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
((2S,3R)-4-(4-Chloro-1,1,2,2,3,3,4,4-Octafluorobutylsulfonyl)-3-(2-Chlorophenyl)-5-Phenyl-2,3-Dihydrofuran-2-Yl)(Phenyl)Methanone is a high-value, structurally complex fluorinated organic intermediate. Its precise stereochemistry and unique perfluoroalkyl sulfonyl group make it a critical building block for advanced chemical synthesis. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced properties.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring metabolic stability.
- Agrochemical Research: Used to develop new generations of herbicides, fungicides, or insecticides where the fluorinated moiety can improve bioavailability and environmental persistence.
- Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique surface properties, such as oil and water repellency.
- Ligand Synthesis: Potential building block for creating chiral ligands used in asymmetric catalysis for the production of enantiomerically pure compounds.
- Advanced Organic Synthesis: Employed in methodological research for constructing complex, polyfunctional molecular architectures under controlled stereochemistry.
Basic Information
| Product Name | ((2S,3R)-4-(4-Chloro-1,1,2,2,3,3,4,4-Octafluorobutylsulfonyl)-3-(2-Chlorophenyl)-5-Phenyl-2,3-Dihydrofuran-2-Yl)(Phenyl)Methanone |
| CAS No. | 771491-59-9 |
| Molecular Formula | C27H16Cl2F8O4S |
| Molecular Weight | 659.37 g/mol |
| Synonyms | (2S,3R)-4-[(4-Chloro-1,1,2,2,3,3,4,4-octafluorobutyl)sulfonyl]-3-(2-chlorophenyl)-5-phenyl-2,3-dihydro-2-furanyl phenyl methanone; (2S,3R)-4-(4-Chloro-1,1,2,2,3,3,4,4-octafluorobutane-1-sulfonyl)-3-(2-chlorophenyl)-5-phenyl-2,3-dihydrofuran-2-yl)(phenyl)methanone; CAS 771491-59-9; Fluorinated Dihydrofuranone Sulfone Derivative; Chiral Fluorinated Sulfone Intermediate. |
| EINECS | Contact for details |
Quality Control
Every batch of ((2S,3R)-4-(4-Chloro-1,1,2,2,3,3,4,4-Octafluorobutylsulfonyl)-3-(2-Chlorophenyl)-5-Phenyl-2,3-Dihydrofuran-2-Yl)(Phenyl)Methanone is produced and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical purity, enantiomeric excess (ee), and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to moisture and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Single Unknown Impurity (HPLC) | ≤ 1.0% |
| Total Impurities (HPLC) | ≤ 3.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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