Description

((2S,3R)-4-(4-Chloro-1,1,2,2,3,3,4,4-Octafluorobutylsulfonyl)-3,5-Diphenyl-2,3-Dihydrofuran-2-Yl)(Phenyl)Methanone is a high-value, structurally complex fluorinated organic intermediate. Its unique molecular architecture, featuring a perfluorinated alkyl chain and multiple chiral centers, makes it a critical building block for advanced chemical synthesis. This compound is primarily sought after by research institutions and pharmaceutical developers for the creation of novel active pharmaceutical ingredients (APIs) and specialty materials where specific stereochemistry and fluorination are required.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of new drug candidates, particularly in areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the introduction of fluorine atoms can significantly alter biological activity and environmental persistence.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals, leveraging its rigid, fluorinated structure to impart unique thermal and chemical resistance properties.
• Catalyst Ligand Development: Acts as a sophisticated ligand precursor for asymmetric catalysis, enabling highly selective chemical transformations in fine chemical manufacturing.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new reactions and methodologies involving sulfones and fluorinated compounds.

Basic Information

Product Name	((2S,3R)-4-(4-Chloro-1,1,2,2,3,3,4,4-Octafluorobutylsulfonyl)-3,5-Diphenyl-2,3-Dihydrofuran-2-Yl)(Phenyl)Methanone
CAS No.	771491-18-0
Molecular Formula	C27H17ClF8O4S
Molecular Weight	624.92 g/mol
Synonyms	(2S,3R)-4-(4-Chloro-1,1,2,2,3,3,4,4-octafluorobutanesulfonyl)-3,5-diphenyl-2,3-dihydrofuran-2-yl(phenyl)methanone; (2S,3R)-4-(4-Chloro-1,1,2,2,3,3,4,4-octafluorobutylsulfonyl)-3,5-diphenyl-2,3-dihydrofuran-2-yl(phenyl)methanone; 771491-18-0; (2S,3R)-4-(4-Chloro-1,1,2,2,3,3,4,4-octafluorobutane-1-sulfonyl)-3,5-diphenyl-2,3-dihydrofuran-2-yl(phenyl)methanone; Benzophenone, 4-[(4-chloro-1,1,2,2,3,3,4,4-octafluorobutyl)sulfonyl]-3,5-diphenyl-2,3-dihydro-2-(2S,3R)-; (2S,3R)-4-(4-Chloro-1,1,2,2,3,3,4,4-octafluorobutylsulfonyl)-3,5-diphenyl-2,3-dihydrofuran-2-yl(phenyl)methanone
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.