Description

(S)-4-Amino-1-Methylpyrrolidin-2-One CAS NO 770706-26-8 is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. This compound is valued for its role as a key building block in the synthesis of complex, biologically active molecules, particularly in the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of novel drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems for stereoselective chemical transformations.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and conformationally restricted scaffolds for drug discovery.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry laboratories worldwide.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(S)-4-Amino-1-Methylpyrrolidin-2-One
CAS No.	770706-26-8
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	(S)-1-Methyl-4-aminopyrrolidin-2-one; (S)-4-Amino-1-methyl-2-pyrrolidinone; (2S)-4-Amino-1-methylpyrrolidin-2-one; (S)-Aminomethylpyrrolidone; (S)-4-Amino-N-methyl-2-pyrrolidone; (S)-1-Methyl-4-aminopyrrolidinone; (S)-4-Amino-1-methyl-2-oxopyrrolidine; (S)-Amino-Methyl-Pyrrolidone
EINECS	Contact for details

Quality Control

Our (S)-4-Amino-1-Methylpyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.