Description

1,1-Cyclopropanedicarboxylicacid,2-Methyl-,Monomethylester,cis-(9Ci) is a high-purity, cis-configured cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. This compound is valued for its rigid, strained three-membered ring structure, which is instrumental in modulating the biological activity and physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the construction of novel herbicides, fungicides, and insecticides, where the cyclopropane ring can enhance stability and bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Material Science Research: Employed in the synthesis of specialized monomers and polymers with unique thermal or mechanical properties derived from the strained ring system.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags to study enzyme function and protein interactions.

Basic Information

Product Name	1,1-Cyclopropanedicarboxylicacid,2-Methyl-,Monomethylester,cis-(9Ci)
CAS No.	767587-88-2
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	cis-2-Methyl-1,1-cyclopropanedicarboxylic acid monomethyl ester; Methyl cis-2-methyl-1,1-cyclopropanedicarboxylate; (1R,2S)-rel-2-Methylcyclopropane-1,1-dicarboxylic acid monomethyl ester; 1,1-Cyclopropanedicarboxylic acid, 2-methyl-, monomethyl ester, cis-; Monomethyl cis-2-methyl-1,1-cyclopropanedicarboxylate
EINECS	Contact for details

Quality Control

Every batch of 1,1-Cyclopropanedicarboxylicacid,2-Methyl-,Monomethylester,cis-(9Ci) is produced and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including chiral purity verification, to ensure compliance with exacting R&D and cGMP standards for advanced intermediates. Comprehensive Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed in a dry and inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.