Description

2-(Trifluoromethyl)Thiophene-3-Carboxylicacid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique structure, featuring both a thiophene ring and a trifluoromethyl group, imparts desirable properties like metabolic stability and enhanced lipophilicity to target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new chemical spaces in fluorochemistry.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Product Name	2-(Trifluoromethyl)Thiophene-3-Carboxylicacid
CAS No.	767337-58-6
Molecular Formula	C6H3F3O2S
Molecular Weight	196.15 g/mol
Synonyms	3-Thiophenecarboxylic acid, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)-3-thiophenecarboxylic acid; 2-Trifluoromethylthiophene-3-carboxylic acid; 2-Carboxy-5-(trifluoromethyl)thiophene; 5-(Trifluoromethyl)thiophene-2-carboxylic acid (isomer check required); α,α,α-Trifluoro-2-thenoic acid; TFTCA
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Thiophene-3-Carboxylicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing identity, purity, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.