Description

1H-Inden-1-Amine,2,3-Dihydro-2-Methoxy-N,n-Dimethyl-,(1S,2R)-(9Ci) is a chiral, stereochemically defined indane derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is pivotal for constructing complex, biologically active molecules with high enantiomeric purity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemical synthesis, where precise stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery programs.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric reactions to introduce the indane core with defined stereochemistry into target molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological profile of lead compounds.
• Fine Chemical Production: Serves as a precursor in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high purity and specific isomerism.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, particularly in studies involving stereoselective synthesis and novel ring systems.

Basic Information

Product Name	1H-Inden-1-Amine,2,3-Dihydro-2-Methoxy-N,n-Dimethyl-,(1S,2R)-(9Ci)
CAS No.	767291-75-8
Molecular Formula	C12H17NO
Molecular Weight	191.27 g/mol
Synonyms	(1S,2R)-2-Methoxy-N,N-dimethyl-2,3-dihydro-1H-inden-1-amine; (1S,2R)-2-Methoxy-N,N-dimethylindan-1-amine; 2,3-Dihydro-2-methoxy-N,N-dimethyl-1H-inden-1-amine, (1S,2R)-rel-; 1H-Inden-1-amine, 2,3-dihydro-2-methoxy-N,N-dimethyl-, (1S,2R)-; (1S,2R)-1-(Dimethylamino)-2-methoxyindane; 767291-75-8; Chiral Indane Amine Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 1H-Inden-1-Amine,2,3-Dihydro-2-Methoxy-N,n-Dimethyl-,(1S,2R)-(9Ci) is characterized and verified for identity, purity, and enantiomeric excess to meet the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) and spectroscopic confirmation are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.