Description

2,3-Dihydro-1H-Isoindol-1-One-4-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile synthetic building block. Its core value lies in its protected boronic acid functionality, which is essential for modern cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecules. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing isoindolinone-based drug candidates with potential therapeutic applications.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds for constructing complex biaryl and heterobiaryl structures in medicinal chemistry.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science Precursor: Serves as a monomer or intermediate for creating organic electronic materials, such as OLEDs or organic semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and target engagement.
• Library Synthesis for Drug Discovery: A valuable reagent for creating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	2,3-Dihydro-1H-Isoindol-1-One-4-Boronic Acid Pinacol Ester
CAS No.	765948-78-5
Molecular Formula	C14H18BNO3
Molecular Weight	259.11 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-isoindol-1-one; 1-Oxo-2,3-dihydro-1H-isoindole-4-boronic acid pinacol ester; 4-Borono-2,3-dihydro-1H-isoindol-1-one pinacol ester; Isoindolin-1-one-4-boronic acid pinacol ester; 4-(Pinacolatoboryl)isoindolin-1-one; CAS 765948-78-5
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1H-Isoindol-1-One-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.