Description

Cyclopentaneacetaldehyde, 2-Formyl-, (1R,2S)- (9Ci) is a high-purity chiral aldehyde building block of significant interest in advanced organic synthesis. Its defined stereochemistry and reactive formyl group make it a critical intermediate for constructing complex, stereodefined molecules where precise spatial orientation is essential. This compound is primarily needed by pharmaceutical R&D and fine chemical sectors for applications in drug discovery and the development of specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Asymmetric Synthesis: Utilized in stereoselective reactions, including aldol condensations and reductive aminations, to introduce the cyclopentane moiety with high enantiomeric purity.
• Fragrance & Flavor Chemistry: Acts as a precursor for synthesizing novel, complex odorants and flavor compounds with unique olfactory properties derived from its bicyclic structure.
• Agrochemical Research: Employed in the development of new chiral pesticides and herbicides, where the specific stereochemistry can influence biological activity and environmental degradation profiles.
• Material Science: Used as a monomer or cross-linking agent in the research of specialty polymers with tailored thermal and mechanical properties.
• Catalyst & Ligand Development: Provides a scaffold for creating novel chiral ligands and organocatalysts used in homogeneous catalysis.

Basic Information

Product Name	Cyclopentaneacetaldehyde, 2-Formyl-, (1R,2S)- (9Ci)
CAS No.	765288-09-3
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	(1R,2S)-2-Formylcyclopentaneacetaldehyde; (1R,2S)-2-Formylcyclopentane-1-acetaldehyde; Bicyclo[3.3.0]octane-2,6-dicarboxaldehyde, (1R,2S)-rel-; rel-(1R,2S)-Bicyclo[3.3.0]octane-2,6-dicarboxaldehyde; (1R,2S)-rel-Bicyclo[3.3.0]octane-2,6-dicarbaldehyde
EINECS	Contact for details

Quality Control

Our Cyclopentaneacetaldehyde, 2-Formyl-, (1R,2S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting R&D standards. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.