Description

2,4,5-Trifluoro-Benzamidine is a high-purity, fluorinated benzamidine derivative, a critical building block in modern organic synthesis. Its value lies in its unique trifluoromethyl-substituted aromatic structure, which imparts enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially protease inhibitors and kinase-targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design of activity-based probes and inhibitors for studying enzymatic mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring fluorinated aromatic amidines.

Basic Information

Product Name	2,4,5-Trifluoro-Benzamidine
CAS No.	764648-43-3
Molecular Formula	C7H5F3N2
Molecular Weight	174.12 g/mol
Synonyms	2,4,5-Trifluorobenzamidine; Benzenecarboximidamide, 2,4,5-trifluoro-; 2,4,5-Trifluorobenzenecarboximidamide; 2,4,5-Trifluoro-benzenecarboximidamide; Amidino-2,4,5-trifluorobenzene
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluoro-Benzamidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.