Description

2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzenemethanol is a versatile and high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in modern herbicides, fungicides, and insecticides, enhancing crop protection efficacy.
• Material Science & OLED Development: Building block for creating novel organic light-emitting diode (OLED) materials, liquid crystals, and conductive polymers due to its boronate functional group.
• Cross-Coupling Reactions: A pivotal reagent in Suzuki-Miyaura cross-coupling, facilitating the efficient and selective formation of biaryl and other conjugated structures.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and sensors for studying biological processes and protein interactions.
• Polymer Chemistry: Monomer or co-monomer for synthesizing specialty polymers with tailored properties for coatings, adhesives, and advanced composites.

Basic Information

Product Name	2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzenemethanol
CAS No.	760989-96-6
Molecular Formula	C13H19BO4
Molecular Weight	250.10 g/mol
Synonyms	5-(Hydroxymethyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; (5-(Hydroxymethyl)-2-hydroxyphenyl)boronic acid pinacol ester; 2-Hydroxy-5-(pinacolatoboryl)benzyl alcohol; Benzenemethanol, 2-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol (5-(hydroxymethyl)-2-hydroxyphenyl)boronate
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzenemethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.